Поисковые системы

Документ взят из кэша поисковой машины. Адрес оригинального документа : http://kodomo.cmm.msu.ru/~lu.andreeva/search.html
Дата изменения: Fri Feb 27 16:44:16 2009
Дата индексирования: Tue Oct 2 02:09:30 2012
Кодировка: Windows-1251
Поисковые слова: поисковая система

Поисковые системы

Учебный сайт Люды Андреевой

Краткое сравнение поисковых систем SRS, MRS и UniProt

Поисковые системы сравнивались по представлениям в них записи SwissProt а также по удобству поиска.

Поиск SRS. Содержит максимально много ссылок. Удобный многофакторный поиск. Информация на странице разбита по темам, к каждой из которых вверху страницы есть ссылка. Красочное поле features, содержащее схему расположения особенностей белка со шкалой длины. Большой выбор представления аминокислотной последовательности.
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Поиск MRs. В описании белка используются только слова из документа, без особых пояснений и расшифровок. Неудачная строка поиска: на мой запрос 'р13001' - Ac моего белка было получено 16 результатов, в числе которых - белки BIOH др организмов. Неудачно поле Features, поскольку при попытке прочитать запись целиком уезжают заголовки и невозможно увидеть описание вторичной структуры целиком. Качественно выполнено описание статей, невыразительная последовательность.
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Поиск UniProt. Удобный поиск, большое количество вариантов оформления страницы. Оглавление сверху для перемещения по странице. Большое количество схем, ссылок (в т.ч. и на 3д структуру). Удобное представление последовательности с нумерацией десятков аминокислот. Не хватает ссылок на статьи.
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Поиск по таксономии в SRS

В поисковой системе SRS для удобства существует страница с описанием поля "Taxonomy" записи в банке SwissProt. С помощью нее можно находить различные данные, находящиеся в соответствующем поле записи, причем поиск может проводиться как с использованием целого слова, так и его части. С помощью этой страницы удалось установить:

На "gam" начинаются таксоны gambusia, gammaherpesvirinae, gammapapillomavirus, gammaproteobacteria, gammaretrovirus, gammaridea.
Английский эквивалент таксона "гамма-протеобактерия" звучит как gammaproteobacteria.
В банке SwissProt находится 83513 записей с описанием белков гамма-протеобактерий.

Поиск в SRS белков с функцией, сходной с BIOH_ECOLI

Формулировка функции белка Строка запроса Количество найденных документов

Carboxylesterase bioH ((([swissprot-Description:Carboxylesterase*] & [swissprot-Description:bioH*]) | [swissprot-Description:Carboxylesterase bioH*]) & [swissprot-Taxonomy:gammaproteobacteria*]) 55

Biotin synthesis protein bioH ((((([swissprot-Description:Biotin*] & [swissprot-Description:synthesis*]) & [swissprot-Description:protein*]) & [swissprot-Description:bioH*]) | [swissprot-Description:Biotin synthesis protein bioH*]) & [swissprot-Taxonomy:gammaproteobacteria*]) 55

Carboxylesterase ([swissprot-Description:Carboxylesterase*] & [swissprot-Taxonomy:gammaproteobacteria*]) 57

Biotin synthesis protein (((([swissprot-Description:Biotin*] & [swissprot-Description:synthesis*]) & [swissprot-Description:protein*]) | [swissprot-Description:Biotin synthesis protein*]) & [swissprot-Taxonomy:gammaproteobacteria*]) 60

Сarboxylesterase activity with a preference for short chain fatty acid esters 0

Carboxylesterase, thioesterase ((([swissprot-Comment:thioesterase*] > parent ) & ([swissprot-Comment:carboxylesterase*] > parent )) & [swissprot-Taxonomy:gammaproteobacteria*]) 55

A complex with CoA, carboxylesterase carboxylesterase 0

A precursor in biotin biosynthesis,carboxylesterase 0

Аминокислотные последователности

В предыдущем пункте шел поиск белков с похожей на BIOH_ECOLI функцией. Воспользовавшись результатами первого из приведенных выше поиска, были найдены аминокислотные последовательности этих белков, которые представлены ниже.

>sp|Q89A54|BIOH_BUCBP Carboxylesterase bioH;
MNKKLHWKSLGTGTTNLILIHGWGVNSKIWSILVQSQLYQHFKLHFVDLPGFGHSNQLLP
MTLNDTAELLSVYIPKNSILLGWSMGGLIASKIALNYPQKIKGIISVCSSPCFIVRPNWP
GIPKKIFLKFYNKLNINFDRTISEFITLQSHNTNYLEIKNLKQQILSQPYPTIYTLKKNL
ETIFKTDLRTKIKKLKIPMLRIYGSLDTFVPKKIREILDILWPKTKSITIAHASHIPFVS
HQKEFYESIINFKNYLNTLKITCQK
>sp|A8AQW5|BIOH_CITK8 Carboxylesterase bioH;
MNDIWWQTEGQGNCHLVLLHGWGLNAEVWNCIREELSAHFTLHLVDLPGFGRSQGFGAMS
LEQMAKHVLKQAPDKAVWLGWSLGGLVASQVALTHPERVQALVTVASSPCFSAREAWPGI
KPDILAGFQQQLSEDFQRTVERFLALQTLGTETARQDARTLKSAVLALPMPEVAVLNGGL
EILKTADLREPLKSLTMPFLRLYGYLDGLVPRKVVPMLDAAWPESESQVFAKAAHAPFIS
HPGEFCQALMALKQKI
>sp|A7ZSU1|BIOH_ECO24 Carboxylesterase bioH;
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALS
LADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGI
KPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGL
EILKTVDLRQPLQNVPMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFIS
HPVEFCHLLVALKQRV
>sp|Q8X716|BIOH_ECO57 Carboxylesterase bioH;
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALS
LAEMAEAVLRQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGI
KPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGL
EILKTVDLRLPLQNVPMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFIS
HPVEFRHVLVALKQRV
>sp|A8A5M0|BIOH_ECOHS Carboxylesterase bioH;
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALS
LADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGI
KPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGL
EILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFIS
HPVEFCHLLVALKQRV
>sp|A1AGT6|BIOH_ECOK1 Carboxylesterase bioH;
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALS
LADMAEAVLRQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGI
KPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGL
EILKTVDLRLPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFIS
HPVEFHHLLVALKQRV
>sp|Q0TC55|BIOH_ECOL5 Carboxylesterase bioH;
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALS
LADMAEVVLRQAPDKAIWLGWSLGGLVASQIALTHPERVLALVTVASSPCFSARDEWPGI
KPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGL
EILKTVDLRLPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFIS
HPVEFHHLLVALKQRV
>sp|Q8FCT4|BIOH_ECOL6 Carboxylesterase bioH;
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALS
LADMAEVVLRQAPDKAIWLGWSLGGLVASQIALTHPERVLALVTVASSPCFSARDEWPGI
KPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGL
EILKTVDLRQPLQNVPMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFIS
HPDEFCHLLVALKQRV
>sp|B1IP53|BIOH_ECOLC Carboxylesterase bioH;
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALS
LADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGI
KPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGL
EILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFIS
HPVEFCHLLVALKQRV
>sp|P13001|BIOH_ECOLI Carboxylesterase bioH;
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALS
LADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGI
KPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGL
EILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFIS
HPAEFCHLLVALKQRV
>sp|Q1R5M2|BIOH_ECOUT Carboxylesterase bioH;
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALS
LADMAEAVLRQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGI
KPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGL
EILKTVDLRLPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFIS
HPVEFHHLLVALKQRV
>sp|A7MGD2|BIOH_ENTS8 Carboxylesterase bioH;
MNDIWWQTTGEGNCHLVLLHGWGLNAEVWRCISQELSSHFTLHLVDLPGYGRSQGYGALT
LDEMARLVASRAPECAIWLGWSLGGLVASQVALSEPSRVDALVTVASSPCFQAGADWPGI
KPEVLSGFQRQLSEDFQRTVERFLALQTLGTETARQDARVLKSIVLAQPMPGADVLNGGL
EILKTADLREALTAWQGPFLRLYGRLDGLVLRKVAALLDARFPDSESQVFEKAAHAPFIS
HPREFCDALLALKARLANR
>sp|Q6CZL9|BIOH_ERWCT Carboxylesterase bioH;
MAALYWQTEGAGNTDLVLLHGWGLNAQVWQSMVVRLAPHFRLHLVDLPGYGRSQGFGPMP
LNDMANIVLTQAPERAVWLGWSLGGLVASQIALSAPLRVEKLITVASSPCFSAQDDWPGI
KPDVLQGFQQQLSEDFQRTVERFLALQTLGTENARQDARLLKGVVLEQPMPSVDVLNGGL
EILREADLRQPLADLTVPLLRLYGALDGLVPRKVAGRLDDEWPNSTSVVMPKAAHAPFIS
HPDAFTEQVIAFAQA
>sp|Q5QZC0|BIOH_IDILO Carboxylesterase bioH;
MSISVTCCGTGTPIVVLHGWGMNSNIWQPVVPALSEHFQLYCVDLPGFGDSVWSSENDVS
LESFIEQIMPALPPRFHLLGWSLGGLIATQIALTHSDRVMSLTTVASSPHFVESNDWAGI
KPDILEQFQQQLDSNFKKTIERFLAIQAMGSEDAREQVKQVKQLIFTKPMPDQGVLKQSL
TILQTADLRQQLPNIEVPFNRFYGRLDSLVPERAIDDISALAPESKAVVFTKSAHAPFIS
EPERFISELLKVVEN
>sp|A6TF35|BIOH_KLEP7 Carboxylesterase bioH;
MNDIWWQTIGEGDCHLVLLHGWGLNAQVWDCITPQLASHFTLHLVDLPGYGRSGGFGAMS
LEAMAQRVLEQAPPQAVWLGWSLGGLVASQVAIMRPERVQALVTVASSPCFAARDDWPGI
KPEVLAGFQQQLSDDFQRTVERFLALQTMGTESARQDARALKQAVLSLPMPSAEALNGGL
EILRTVDLRQALVRLPMPFLRLYGRLDGLVPRKIVPLLDDLWPESESILFDKAAHAPFVS
HPAAFCEPLLALKTRLG
>sp|Q5X590|BIOH_LEGPA Carboxylesterase bioH;
MNIHLDKHGQGMPLVLFHGWGFDNQIWQPIIPYLKPKYQIILVDLPGFGLTPMMDWESFK
KNLLDQLPDKFALAGWSMGGLYATRLAIEEPARVQYLINITSSPRFISDIDWPGVAEEVF
VNFYNNLSKDINKTLKEFISLQLNKMKFDFKIGNPPSPEGLAFGLEILGTWDFREQLKQI
TIPTVYLFGRLDPITPVKTMAIMEKNYPNFKYVLFNRAAHMPFLSHTDLFITMMDEFIK
>sp|A5IBW4|BIOH_LEGPC Carboxylesterase bioH;
MNIHLDKYGQGMPLVLFHGWGFDSQIWQPIIPYLKPKYQIILVDLPGFGLTPMMDWESFK
KNLLDQLPDKFALAGWSMGGLYATRLAIEEPARVQYLINITSSPRFISDVDWPGVAEEVF
VNFYNNLSKDINKTLKEFISLQLNKMKFDFKIGNPPSPEGLAFGLEILGTWDFREQLKQI
SIPTVYLFGRLDPITPAKTMAIMEKNYPNFKYVLFNRAAHMPFLSHTDLFITMMDEFIK
>sp|Q5ZVG6|BIOH_LEGPH Carboxylesterase bioH;
MNIHLDKYGQGMPLVLFHGWGFDSQIWQPIIPYLKPKYQIILVDLPGFGLTPMMDWESFK
KNLLDQLPDKFALAGWSMGGLYATRLAIEEPARVQYLINITSSPRFISDIDWPGVAEEVF
VNFYNNLSKDINKTLKEFISLQLNKMKCDFKIGNPPSPEGLAFGLEILGTWDFREQLKQI
SIPTVYLFGRLDPITPVKTMAIMEKNYPNFKYVLFNRAAHMPFLSHTDLFITIMDEFIK
>sp|Q5WW99|BIOH_LEGPL Carboxylesterase bioH;
MNIHLDKHGQGMPLVLFHGWGFDSQIWQPIIPYLKPKYQIILVDLPGFGLTPMMDWESFK
KNLFDQLPDKFALAGWSMGGLYATRLAIEEPARVQYLINITSSPRFISDIDWPGVAEEVF
VNFYNNLSKDINKTLKEFISLQLNKMKFDFKIGNPPSPEGLAFGLEILGTWDFREQLKQI
SIPTVYLFGRLDPITPAKTMAIMEKNYPNFKYVLFNRAAHMPFLSHTDLFITMMDEFIK
>sp|Q609V0|BIOH_METCA Carboxylesterase bioH;
MGLFIETSGRGPEVVLIHGWGMHGGIWSGFVPWLTDRFRVTRIDLPGHGHSPMLADWSLE
TVAGAVLEAVPRPAHWVGWSLGAMVALEAARMAPGAVASLTLLCGTPRFVAEPGWPGMEA
VTLMRFADGFLSDYEDACRRFLALQAWGMPNERELLRGVRSQLSGRPPPERPALLAGLEV
LRHADLRGVLRELPQPVQALLGRRDRLVPVELGDALARLKTGLVSHRIDDAPHVPFLTHG
ERTARLIHEFIASS
>sp|Q7N9V7|BIOH_PHOLL Carboxylesterase bioH;
MADLFWQTSDEGSRDLVLLHGWGLNAEVWRSIEMRCAPHFRLHLVDLPGYGRSQKYGPMN
LADMADEVWRYAPENALWLGWSLGGLVASRIALDHQDKVAGLITVASSPHFSAESDWPGI
KPEVLHDFEHQLSKDFQRTVERFLALQTLGTDSARQDARLLKSVVLAQPMPSVEVLHVGL
EILRTEDLRQPLAELAIPFLRIYGYLDGLVPRKIINILDEKWPRSVSAMMRHAAHAPFIS
HPDEFVGLLTEFASREVLQGR
>sp|Q6LVQ7|BIOH_PHOPR Carboxylesterase bioH;
MTTALCWQTEGQGSDLVLIHGWGMNGAVWQQLLPLLTPFYRVHWVDMPGYGHSHDISADS
IEEMAQLLLDKSPISATWLGWSLGGLVATQAALLAPERVTRLVTVASSPRFAAEGTWRGI
QPQVLDDFRRQLGDDFQLTVERFLALQAMGSPTARQDIKLLKQAVLSRPQPNPEALSIGL
RLLADVDLRAQLGDITQPWLRLYGRLDGLVPAKVAKDMDQLAPQSCRQIFAAASHAPFIS
HPEEFVQTLKDFIK
>sp|Q15N09|BIOH_PSEA6 Carboxylesterase bioH;
MHTTLKTRTVGSGPNFVLLHGWGVNSGVWQPIAKQLEQHFSVTYVDLPGFGENNQIMPKP
YDLKNLAECVANVLPENSVLAGWSLGGLVAQHVALLEPTNVKQLILIATSPKFQKGNDWA
GIDPNILQAFSQQLVKNLSKTIERFLAIQAMGSDSAKTDIRKIKNSIEASPQADIAALTA
GLDILEHVDLRDQIAALKMPIHWMLGRLDSLVPVKLQGYVQRSLAKNHSVTIFPHASHAP
FISHTEDFLIDLMENTLR
>sp|A9MMB5|BIOH_SALAR Carboxylesterase bioH;
MNDIWWQTYGEGNCHLVLLHGWGLNAEVWHCIREELGSHFTLHLIDLPGYGRSTGFGAMT
LEEMTAQVAKNAPDQAIWLGWSLGGLVASQMALIHPERVQALVTVASSPCFSAREGWPGI
KPEVLAGFQQQLSDDFERTVERFLALQTLGTETARQDARTLKSVVLAQSMPDVEVLNGGL
EILKTVDLREPLKSVNMPFLRLYGYLDGLVPRKIAPLLDTLWPHSTSQIIVKAAHAPFIS
HPAAFCQALAALKSSL
>sp|Q57IW5|BIOH_SALCH Carboxylesterase bioH;
MNDIWWQTYGEGNCHLVLLHGWGLNAEVWHCIREELGSHFTLHLVDLPGYGRSSGFGAMT
LEEMTAQVAKNAPDQAIWLGWSLGGLVASQMALTHPERVQALVTVASSPCFSAREGWPGI
KPEILGGFQQQLSDDFQRTVERFLALQTLGTETARQDARTLKSVVLAQPMPDVEVLNGGL
EILKTVDLREALKNVNMPFLRLYGYLDGLVPRKIAPLLDTLWPHSTSQIMAKAAHAPFIS
HPAAFCQALMTLKSSL
>sp|Q5PLY8|BIOH_SALPA Carboxylesterase bioH;
MNDIWWQTYGEGNCHLVLLHGWGLNAEVWHCIREELGSHFTLHLVDLPGYGRSSGFGAMT
LEEMTAQVAKNAPDQAIWLGWSLGGLVASQMALTHPERVQALVTVASSPCFSAREGWPGI
KPEILGGFQQQLSDDFQRTVERFLALQTLGTETARQDARTLKSVVLAQPMPDVEVLNGGL
EILKTVDLREALKNVNMPFLRLYGYLDGLVPRKIAPLLDTLWPHSTSQIMAKAAHAPFIS
HPAAFCQALMTLKSSL
>sp|Q8Z221|BIOH_SALTI Carboxylesterase bioH;
MNDIWWQTYGEGNCHLVLLHGWGLNAEVWHCIREELGSHFTLHLVDLPGYGRSSGFGAMT
LEEMTAQVAKNAPDQAIWLGWSLGGLVASQMALTHPERVQALVTVASSPCFSAREGWPGI
KPEILGGFQQQLSDDFQRTVERFLALQTLGTETARQDARTLKSVVLAQPMPDVEVLNGGL
EILKTVDLREALKNVNMPFLRLYGYLDGLVPRKIAPLLDTLWPHSTSQIMAKAAHAPFIS
HPAAFCQALMTLKSSL
>sp|Q8ZLI9|BIOH_SALTY Carboxylesterase bioH;
MNDIWWQTYGEGNCHLVLLHGWGLNAEVWHCIREELGSHFTLHLVDLPGYGRSSGFGAMT
LEEMTAQVAKNAPDQAIWLGWSLGGLVASQMALTHPERVQALVTVASSPCFSAREGWPGI
KPEILGGFQQQLSDDFQRTVERFLALQTLGTETARQDARTLKSVVLAQPMPDVEVLNGGL
EILKTVDLREALKNVNMPFLRLYGYLDGLVPRKIVPLLDTLWPHSTSQIMAKAAHAPFIS
HPAAFCQALMTLKSSL
>sp|Q8GHL1|BIOH_SERMA Carboxylesterase bioH;
MTALYWQTIGEGERDLVLLHGWGLNAEVWSCIQALTPHFRLHLVDLPGYGRSQGFGALSL
AQMTEIVLAAAPPQAWWLGWSLGGLVASQAALMQPQRVSGLITVASSPCFAARDEWPGIR
PDVLSGFQHQLSLDFQRTVERFLALQTLGTESARQDARQLKAVVLNQPTPSVEVLNGGLE
ILRTADLRAPLAELNLPLLRIYGYLDGLVPRKVAELLDAAWPNSTSQIVAKAAHAPFISH
PDEFVTMIEAFIAAH
>sp|A8GKT5|BIOH_SERP5 Carboxylesterase bioH;
MTALYWQTIGEGDRDLVLLHGWGLNAEVWSCMLERLTPHFRLHLVDLPGYGRSQGFAAMS
LEQMAEIVLDAAPAQAWWLGWSLGGLVASQIALTQPQRVHGLITVASSPCFAAQDDWPGI
RPEVLSGFQHQLSQDFQRTVERFLALQTLGTESARQDARLLKSVVLNQPMPSVEILNGGL
EILRTADLRQSLAGLSLPLLRIYGYLDGLVPRKVAGLLDVSWPHSSSIIIAKAAHAPFIS
QPDEFAEIIGTFVAENGICRQNAQ
>sp|Q8E8N6|BIOH_SHEON Carboxylesterase bioH;
MNATTSAHHPLHIETIGQGPDLVVIHGWGVNSAVFTPLHEQLSEYRVHYVDLPGFGLSQP
IAGNLSTWIDALINNLPTNAIWAGWSLGGLVATQAAIDYPSHIKGLITIASSPCFMAREE
EAWPGIPPQVLSMFGEQLGQNLPKTIERFLAIQAMGSETAKEDIKQLRDLVLARPLPDAA
ALTQGLDMLNQIDLRMQLSSISQPWLRIWGRLDGLVPKRVQPQMPTASHITDVMLAKASH
APFVSHRQEFLQALLPWLTQFKD
>sp|Q0HPU6|BIOH_SHESR Carboxylesterase bioH;
MNATTPAHRPQLHIDTRGQGPDLVMLHGWGVNSAVFTPLHEQLSEYRVHYVDLPGFGLSQ
PIAGDLSTWVDALIHALPANAIWAGWSLGGLVATQAAIRYPSHIQGLITIASSPCFMARE
EEAWPGIPPQVLSMFGEQLGQNLPKTIERFLAIQAMGSETAKDDIKQLRDLVLARPLPDA
AALTQGLDMLNQIDLRPQLSAIQQPWLRIWGRLDGLVPKRVQPQMPTANHITDVMLAKAS
HAPFVSHMEEFLQAITPWLAQFKD
>sp|Q31VM0|BIOH_SHIBS Carboxylesterase bioH;
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSQGFGALS
LADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDDWPGI
KPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGL
EILKTVDLRQPLQNVPMPFLRLYGYLDGLVPRKVVPMLDKLWPRSKSYIFAKAAHAPFIS
HPVEFCHLLVALKQRL
>sp|Q32AM6|BIOH_SHIDS Carboxylesterase bioH;
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGAMS
LADMAEAVLRQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWLGI
KPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGL
EILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFIS
HPVEFRHVLVALKQRV
>sp|Q83PW0|BIOH_SHIFL Carboxylesterase bioH;
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALS
LADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGI
KPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGL
EILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFIS
HPVEFCHLLVALKQRVLVVSES
>sp|Q3YWL3|BIOH_SHISS Carboxylesterase bioH;
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSQGFGALS
LADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDDWPGI
KPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGL
EILKTVDLRQPLQNVPMPFLRLYGYLDGLVPRKVVPMLDKLWPRSKSYIFAKAAHAPFIS
HPVEFCHLLVALKQRV
>sp|Q2NQH6|BIOH_SODGM Carboxylesterase bioH;
MVSLFWQTTGTGDRDLVLLHGWGLNAEVWSYIVPRLATHFRLHLVDLPGYGRSRGYGALT
LEEMAEEVASRAPHGALWLGWSLGGLVATTVARRCPHAVAGLVTVASSPRFCADGDWPGI
RPEVLEGFARELRQDFTRTVSRFLGLQTLGTASARQDTRWLKSVVLAHPAPAIEVLTGGL
ALLRTSDVRKALDQLDVPLLRLYGYLDGLVPRKVVPLVDELSTASHSIVFAGAAHAPFIS
HPVPFCQALCDFSQLES
>sp|Q9KNL4|BIOH_VIBCH Carboxylesterase bioH;
MTMALYWQVSGQGQDLVLVHGWGMNGAVWQQTAQALSDHFRVHVVDLPGYGHSAEQHAAS
LEEIAQALLEHAPRNAIWVGWSLGGLVATHMALHHSDYVSKLVTVASSPKFAAQGSWRGI
QPDVLTAFTDQLVADFQLTIERFMALQAMGSPSARQDVKVLKQAVLSRPMPNPQSLLAGL
TMLAEVDLRDELQHISVPMLRLYGRLDGLVPAKVARDLNHLAPYSEAFMFDQSSHAPFMT
EAEAFCQQLIEFATR
>sp|Q5E8N3|BIOH_VIBF1 Carboxylesterase bioH;
MTTPLYWQTEGEGSDLVLIHGWGMNGAVWQTTSEKLSQHYRVHTVDLSGYGHSAELGCAD
FDEMVKQVLAQAPKKAAWLGWSLGGLIATKAALTSPERVSQLITVASSPRFSAEKGWRGI
KPLVLSQFTEQLKTDFTLTVERFMALQAMGSPNAKQDIKLVKKAVFSRPMPDQQALATGL
MILADIDLREAVSQLSMPVCRMYGRLDGLVPIKVAHDMDELMPNSAKIVFEQASHAPFIS
HNDEFISELRTFLNQHA
>sp|A7MST3|BIOH_VIBHB Carboxylesterase bioH;
MSTNLHWQSFGQGPDLVLLHGWGMNGAVWQQTVESLQPYFRVHVVDLPGYGHSAESHAED
LAKIADLVLQDAPEKAVWLGWSLGGLVATHIALNAPQRVSKLITVASSPKFAAERPWRGI
QPNVLTAFTDQLLEDFSVTIERFMALQAMGSPSARKDVKQLKQAVLSRPQPNPDSLLVGL
NILADVDLRDALTSLSMPMLRLYGRLDGLVPIKVASDLNEQLPSTQQFVFNQSSHAPFMT
EHEAFCLQVREFAA
>sp|Q87TC2|BIOH_VIBPA Carboxylesterase bioH;
MSTNLHWQSFGQGPDLVLLHGWGMNGAVWQQTVESLQADFCVHVVDLPGYGFSAEHHGED
LAQIAAMVLKDAPEKAVWLGWSLGGLVATHIALNAPQRVSKLITVASSPKFAAEKPWRGI
QPNVLSAFTSQLLEDFSLTIERFMALQAMGSPSARKDVKQLKQAVLSRPQPNPESLLVGL
NILADVDLRDALISLTMPMLRLYGRLDGLVPIKVATDLSQQLPHTQQFVFSQSSHAPFMT
EHDEFCAQVRDFAQD
>sp|Q8DDU4|BIOH_VIBVU Carboxylesterase bioH;
MSTDLHWQTQGQGPDLVLLHGWGMNGAVWQQVVERLELHFRLHVVDLPGYGHSAHLHAAS
LEEIAQQLLEHAPKQAIWVGWSLGGLVATHMALHHADYVSKLVTVASSPKFAAEARWRGI
QPQVLSAFTEQLSEDFHTTVERFMALQAMGSPSARQDVKNLKQAVFSRPQPNPQSLLAGL
QMLAEVDLRDHLPHLTMPMLRLYGRLDGLVPIKVAQDLEKVLPASEQFIFTQSSHAPFIT
EPESFCHQLLSFAGK
>sp|Q7MPY0|BIOH_VIBVY Carboxylesterase bioH;
MSTDLHWQTQGQGPDLVLLHGWGMNGAVWQQVVERLEPHFRLHVVDLPGYGHSAHLHAAS
LEEIAQQLLEHAPKQAIWVGWSLGGLVATHMALHHADYVSKLVTVASSPKFAAEARWRGI
QPQVLSAFTEQLSEDFHITVERFMALQAMGSPSARQDVKNLKQAVFSRPQPNPQSLLAGL
QMLAEVDLRDHLPHLTMPMLRLYGRLDGLVPIKVAQDLEKALPASEQFIFTQSSHAPFIT
EPESFCHQLLSFAGK
>sp|Q8D1X1|BIOH_WIGBR Carboxylesterase bioH;
MKPFFWRIIGSGSVNLVFIHGWGLNSCIWNNIIIILSNYFKLHLVDLPGYGKNILYKEYS
FSKITEIIACKSPKKSILIGWSLGGLIATNISIVYPEKFKGLIIVSSSPCFCEKKDWPGI
KKEILNNFSFQLKNDFHNTVKKFFNIQFLGTKKNNNEIKKLKNIFFRQKEPSYKTLSSGL
KILKNIDIRNYLKYIKIPTLRIYGNLDVIVPVKIIPIIKKLQNFNINKNIIIPSASHAPF
LSHPFLFCKIIKYFIKKFN
>sp|Q8PQE0|BIOH_XANAC Carboxylesterase bioH;
MHIDVIGHGPALVLLHGWALHGGVFAPLVERLAPHYQLHLVDLPGHGFSRDDSTPLALPY
VVAEIAAATPPAVWLGWSLGGLFALHAAATLPQVRGLAMIAATPRFVRGSDWPSAVQREV
FVQFGVELSRDYRGTLERFLALDTLGSAHARSELRSLRETLTARGEPAPEALQQGLTLLE
RTDLRRTVPQLARPSLWIAGQRDRLVPAAGMHAAAALSPHAQALTIAGGGHAPFLGHADQ
VSEALQRFVASVP
>sp|Q4UZP1|BIOH_XANC8 Carboxylesterase bioH;
MHIDVIGHGPALVLLHGWALHGGVFAPLVERLAPHYQLHLVDLPGHGFSHDDTTPLALPH
VVAAIAAATPAAVWVGWSLGGLFALHAAATQPQVRALAMIAATPRFVRGSDWPDAVEREV
FVQFGQDLARDYRGTLDRFLALDTLGSAHARSELRSLRETLTARGEPAASALQDGLGLLE
RTDLRRALATLARPSLWIAGQRDRLVPAAGMHAAAARAPHAQALTIDGGGHAPFLGHADQ
VAEALHRFVAALP
>sp|Q8PDF3|BIOH_XANCP Carboxylesterase bioH;
MHIDVIGHGPALVLLHGWALHGGVFAPLVERLAPHYQLHLVDLPGHGFSHDDTTPLALPH
VVAAIAAATPAAVWVGWSLGGLFALHAAATQPQVRALAMIAATPRFVRGSDWPDAVEREV
FVQFGQDLARDYRGTLDRFLALDTLGSAHARSELRSLRETLTARGEPAASALQDGLGLLE
RTDLRRALATLARPSLWIAGQRDRLVPAAGMHAAAARAPHAQALTIDGGGHAPFLGHADQ
VAEALHRFVAALP
>sp|Q2P907|BIOH_XANOM Carboxylesterase bioH;
MHIDVIGHGPALVLLHGWALHGGVFAPLVERLAPHYQLHLVDLPGHGFSRDDSTPLALPY
VVAEIAAATPPAVWLGWSLGGLFALHAAATLPQVRGLAMIAATPRFVRGSDWPDAVQREL
FVQFGTELSRDYRGTLERFLALDTLGSAHARSELRSLRETLTARGEPAPEALQQGLSLLE
RTDLRRALPQLARPSLWIAGQRDRLVPAAGMHAAAALSPHAQALTIAGGGHAPFLGHADQ
VSEALQRFVASVP
>sp|Q5H6D1|BIOH_XANOR Carboxylesterase bioH;
MHIDVIGHGPALVLLHGWALHGGVFAPLVERLAPHYQLHLVDLPGHGFSRDDSTPLALPY
VVAEIAAATPPAVWLGWSLGGLFALHAAATLPQVRGLAMIAATPRFVRGSDWPDAVQREL
FVQFGTELSRDYRGTLERFLALDTLGSAHARSELRSLRETLTARGEPAPEALQQGLSLLE
RTDLRRALPQLARPSLWIAGQRDRLVPAAGMHAAAALSPHAQALTIAGGGHAPFLGHADQ
VSEALQRFVASVP
>sp|Q9PDM3|BIOH_XYLFA Carboxylesterase bioH;
MYIEVTGYGPALVLIHGWAMHSGVFAPLVEQLRAHHTLYLVDLPGHGYNHTTLTPLALPH
VVHAIAAATPPAVWLGWSLGGLFALHAAATLPQVRGLIMLAATPCFVRREDWPHAVEVSI
FTQFAEDLKQNYTETINRFLALDTLGSTYAQSELRQLRQILNARHTPNTATLQAGLELLA
HTDLRRAVIDLTPPSLWIAGQRDRLVPAASIHAATALAPSGQTELLTITGGGHAPFLSHA
NQMTAALQHFIATLP
>sp|Q87DT3|BIOH_XYLFT Carboxylesterase bioH;
MYIEVTGYGPALVLIHGWAMHSGVFAPLVEQLRPHHTLYLVDLPGHGYNHTTPTPLALPQ
VVHAIAAATPPAVWLGWSLGGLFALHAAATLPQVRGLIMLAATPCFVRREDWPHAVEVSI
LTQFAQDLKQNYTETINRFLALDTLGSTHAQSELRQLRKILNARHTPNTATLQAGLELLA
HTDLRRALIDLTPPSLWIAGQRDRLVPAASIQAATVLAPSDQTELLTITGGGHAPFLSHA
NQMTAALQHFIATLP
>sp|A1JSF8|BIOH_YERE8 Carboxylesterase bioH;
MKQLYWNICGEGDCDLVLLHGWGLNAGVWHCIIDRLTPHFRLHLVDLPGYGRSTEFGAMS
LSEMAEIVLQQAPQQAIWLGWSMGGLVASQIALSHPERVRGLITVSSSPCFTAHDEWPGI
RPEVLAGFQQQLSEDFQRTVERFLALQTLGTESARQDARLLKAVVLQHQMPEVAVLTGGL
DILRTADLREELADCSLPFLRIYGYLDGLVPRKVAALLNSQWPHTQSVVMPGSAHAPFVS
HPEAFSQLVVDFAQQSNT
>sp|A7FNV8|BIOH_YERP3 Carboxylesterase bioH;
MKQLYWYTCGEGDCDLVLLHGWGLNSGVWHCIIDRLAPHFRLHLVDLPGYGRSQDYGAMS
LADMAERVAQQAPKQALWLGWSMGGLVASQIALSQPECVRGLITVSSSPCFTARDEWPGI
KPEVLAGFQHQLSDDFHRTVERFLALQTLGTESSRQDARLLKSVVLQHQMPDVEVLTGGL
AILRTADLRTALAGFTLPFMRVYGHLDSLVPRKVASLLDSAWPQTQSVVMQGAAHAPFIS
HPNDFAKLILNFAEENKK
>sp|Q74Y45|BIOH_YERPE Carboxylesterase bioH;
MKQLYWYTCGEGDCDLVLLHGWGLNSGVWHCIIDRLAPHFRLHLVDLPGYGRSQDYGAMS
LADMAERVAQQAPKQALWLGWSMGGLVASQIALSQPECVRGLITVSSSPCFTARDEWPGI
KPEVLAGFQHQLSDDFHRTVERFLALQTLGTESSRQDARLLKSVVLQHQMPDVEVLTGGL
AILRTADLRTALAGFTLPFMRVYGHLDSLVPRKVASLLDSAWPQTQSVVMQGAAHAPFIS
HPNDFAKLILNFAEENKK
>sp|Q664J8|BIOH_YERPS Carboxylesterase bioH;
MKQLYWYTCGEGDCDLVLLHGWGLNSGVWHCIIDRLAPHFRLHLVDLPGYGRSQDYGAMS
LADMAERVAQQAPKQALWLGWSMGGLVASQIALSQPECVRGLITVSSSPCFTARDEWPGI
KPEVLAGFQHQLSDDFHRTVERFLALQTLGTESSRQDARLLKSVVLQHQMPDVEVLTGGL
EILRTADLRTALSGFTLPFMRVYGHLDSLVPRKVASLLDSAWPQTQSVVMQGAAHAPFIS
HPNDFAKLILNFAEENKK

Формулировка функции белка	Строка запроса	Количество найденных документов
Carboxylesterase bioH	((([swissprot-Description:Carboxylesterase] & [swissprot-Description:bioH]) \| [swissprot-Description:Carboxylesterase bioH]) & [swissprot-Taxonomy:gammaproteobacteria])	55
Biotin synthesis protein bioH	((((([swissprot-Description:Biotin] & [swissprot-Description:synthesis]) & [swissprot-Description:protein]) & [swissprot-Description:bioH]) \| [swissprot-Description:Biotin synthesis protein bioH]) & [swissprot-Taxonomy:gammaproteobacteria])	55
Carboxylesterase	([swissprot-Description:Carboxylesterase] & [swissprot-Taxonomy:gammaproteobacteria])	57
Biotin synthesis protein	(((([swissprot-Description:Biotin] & [swissprot-Description:synthesis]) & [swissprot-Description:protein]) \| [swissprot-Description:Biotin synthesis protein]) & [swissprot-Taxonomy:gammaproteobacteria*])	60
Сarboxylesterase activity with a preference for short chain fatty acid esters		0
Carboxylesterase, thioesterase	((([swissprot-Comment:thioesterase] > parent ) & ([swissprot-Comment:carboxylesterase] > parent )) & [swissprot-Taxonomy:gammaproteobacteria*])	55
A complex with CoA, carboxylesterase	carboxylesterase	0
A precursor in biotin biosynthesis,carboxylesterase		0

Учебный сайт Люды Андреевой

Краткое сравнение поисковых систем SRS, MRS и UniProt

Поиск по таксономии в SRS

Поиск в SRS белков с функцией, сходной с BIOH_ECOLI

Аминокислотные последователности

Мной также были выполнены дополнительные задания.