On UT 2001 September 14-18, we used the MOSAIC II imager on the CTIO 4m Blanco telescope to obtain deep U-band observations of the CDF-S/GOODS field. ... Here we decribe the observations and the data processing, and make available the initial, version 0.5 ("best effort") release of the reduced image. ... Visual comparison of image quality between CTIO and EIS U-band imaging data of the CDF-S . ... The EIS CDF-S U-band images have comparable sensitivity to the CTIO data, but with better image quality. ...