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Moscow University Chemistry Bulletin Vol. 46, No. 6, P. 382 (2005)
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S. A. Yamashkin, EA. Oreshkina, M. A. Yurovskaya

About the possibility of using of 5-, 6-amino-2,3,7-trimethyl-, 1,2,3,7-tetramethylindoles in synthesis of trifluoromethylpyrroloquinolones

Abstract

It was showed that 5-, 6-amino-2,3,7-trimethyl- and 5-, 6-amino-l,2,3,7-tetramethylindoles react with the trifluoroethylacetoacetat, in boiling benzene with formation corresponding amides, wich cyclizate into corresponding trifluoromethylpyrroloquinolones in trifluoroacetic acid, exepting amide from 5-amino-l,2,3,7-tetramethylindole, wich don’t cyclizate by the long boiling in trifluoroacetic acid.
Moscow University Chemistry Bulletin.
2005, Vol. 46, No. 6, P. 382
   

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