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UNIVERSITY OF MICHIGAN | COLLEGE OF PHARMACY
| MOSBERG LAB

PDB ID or protein name

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* ABOUT OPM
* DOWNLOAD OPM FILES
* CONTACT US
* LIPID COMPOSITION ATLAS

* Protein Classification

* *Types* (4 types)
* *Classes* (11 classes)
* *Superfamilies* (211 superfamilies)
* *Families* (309 families)
* *Species* (298 species)
* *Localization* (22 types)
* *All proteins in OPM* (902 entries)


* Protein Links

* PDB Sum ,
* PDB ,
* MSD ,
* SCOP ,
* Swiss-Prot ,
* Pfam ,
* OCA ,
* MMDB


2QTS ТЛ Acid-sensing ion channel

2qts ТЛ Acid-sensing ion channel
Magnify 2qts ТЛ Acid-sensing ion channelEnlarged view of image

3D view in Chime , Jmol

or Webmol

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Download Coordinates

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/Topology in Eukaryotic plasma membrane/
Topology *extracellular side*
*cytoplasmic side*

* /Type:/ 1. Transmembrane (2 classes)
* /Class:/ 1.1. Alpha-helical transmembrane
(57 superfamilies)
* /Superfamily:/ 1.1.42. Epithelial sodium channel (ENaC)
(1 family) 1.A.6 (TCDB)

* /Family:/ 1.1.42.01. Acid-sensing ion channels
(1 protein) 1.A.6 (TCDB)

* /Species:/ /Gallus gallus / (9
proteins)
* /Localization:/ Eukaryotic plasma membrane
(199
proteins)

2qts ТЛ Acid-sensing ion channel
*Hydrophobic Thickness* 37.5 ТБ 2.2 У?
*Tilt Angle* 13 ТБ 2ТА
*Ю?G_transfer * -76.9 kcal/mol
*Links to 2qts* PDB Sum
,
SCOP , MSD
, OCA
, MMDB
, Dali

*Topology* subunit A (N-terminus cytoplasmic)
*Resolution* 1.90 У?
*Related PDB Sum entries* 3hgc
,
3ij4


*Number of TM Secondary Structures* 6

3 transmembrane subunits
*A* - Tilt: 5ТА - Segments: 1(45-70), 2(427-452)
*B* - Tilt: 23ТА - Segments: 1(43-70), 2(427-453)
*C* - Tilt: 23ТА - Segments: 1(41-67), 2(427-453)

Comments on 2QTS ТЛ Acid-sensing ion channel
Asymmetric trimer.


Copyright Т? 2005- Andrei Lomize , Mikhail Lomize
and Irina Pogozheva
University of Michigan, Ann Arbor, MI 48109 USA
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