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Дата изменения: Thu Dec 24 00:46:44 2009
Дата индексирования: Tue Oct 2 18:15:17 2012
Кодировка:
Can stimulate E2F-dependent transcription. Binds DNA cooperatively
with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3',
found in the promoter region of a number of genes whose products are involved
in cell cycle regulation or in DNA replication. The DP2/E2F complex functions
in the control of cell-cycle progression from G1 to S phase.
The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.