Документ взят из кэша поисковой машины. Адрес оригинального документа : http://kodomo.cmm.msu.ru/~mikhail88/term3/EMBL.files/x01631.txt Дата изменения: Tue Sep 12 17:33:10 2006 Дата индексирования: Sat Dec 22 07:03:36 2007 Кодировка:

ID X01631; SV 1; linear; genomic DNA; STD; PRO; 14526 BP.
XX
AC X01631;
XX
DT 07-NOV-1985 (Rel. 07, Created)
DT 15-MAR-2006 (Rel. 87, Last updated, Version 19)
XX
DE E. coli origin of replication oriC and genes gid, unc, EcoURF-1 and glmS
XX
KW inverted repeat; origin of replication; transposable element.
XX
OS Escherichia coli
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC Enterobacteriaceae; Escherichia.
XX
RN [1]
RP 1-14526
RX PUBMED; 6395859.
RA Walker J.E., Gay N.J., Saraste M., Eberle A.N.;
RT "DNA sequence around the Escherichia coli unc operon";
RL Biochem. J. 224(3):799-815(1984).
XX
RN [2]
RP 1-14526
RX PUBMED; 1291230.
RA Messer W., Hartmann-Kuehlein H., Langer U., Mahlow E., Roth A., Schaper S.,
RA Urmoneit B., Woelker B.;
RT "The complex for replication initiation of Escherichia coli.";
RL Chromosoma 102(1 Suppl):S1-S6(1992).
XX
FH Key Location/Qualifiers
FH
FT source 1..14526
FT /organism="Escherichia coli"
FT /mol_type="genomic DNA"
FT /db_xref="taxon:562"
FT CDS <1..28
FT /codon_start=2
FT /transl_table=11
FT /note="16K protein"
FT /db_xref="GOA:P03817"
FT /db_xref="HSSP:P00388"
FT /db_xref="UniProtKB/Swiss-Prot:P03817"
FT /protein_id="CAA25772.1"
FT /translation="GSWVNLLK"
FT rep_origin 65..296
FT /note="min. region of oriC"
FT promoter 343..348
FT /note="pot. promoter -35 region"
FT promoter 367..372
FT /note="pot. promoter -10 region"
FT RBS 395..398
FT /note="pot. Shine Dalgarno region"
FT CDS 407..2293
FT /transl_table=11
FT /note="gidA protein"
FT /db_xref="GOA:P0A6U3"
FT /db_xref="UniProtKB/Swiss-Prot:P0A6U3"
FT /protein_id="CAA25773.1"
FT /translation="MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQM
FT SCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLY
FT RQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKI
FT HIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQHGDN
FT PMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRYCPSIE
FT DKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPG
FT YAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSADKE
FT GWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEIGRELGLV
FT DDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREASGEDLLRPEM
FT TYEKLTTLTPFAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYR
FT QVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGMLRRSA"
FT repeat_unit 2305..2330
FT /note="pot. hairpin structure"
FT RBS 2346..2349
FT /note="pot. Shine Dalgarno region"
FT CDS 2357..2980
FT /transl_table=11
FT /note="gidB protein"
FT /db_xref="GOA:P0A6U5"
FT /db_xref="InterPro:IPR003682"
FT /db_xref="PDB:1JSX"
FT /db_xref="UniProtKB/Swiss-Prot:P0A6U5"
FT /protein_id="CAA25774.1"
FT /translation="MLNKLSLLLKDAGISLTDHQKNQLIAYVNMLHKWNKAYNLTSVRD
FT PNEMLVRHILDSIVVAPYLQGERFIDVGTGPGLPGIPLSIVRPEAHFTLLDSLGKRVRF
FT LRQVQHELKLENIEPVQSRVEEFPSEPPFDGVISRAFASLNDMVSWCHHLPGEQGRFYA
FT LKGQMPEDEIALLPEEYQVESVVKLQVPALDGERHLVVIKANKI"
FT promoter 3474..3479
FT /note="pot. -35 region"
FT promoter 3500..3505
FT /note="pot. -10 region"
FT misc_feature 3512
FT /note="pot. transcription start site (unc)"
FT CDS 3585..3977
FT /transl_table=11
FT /note="uncI protein"
FT /db_xref="GOA:P0ABC0"
FT /db_xref="UniProtKB/Swiss-Prot:P0ABC0"
FT /protein_id="CAA25775.1"
FT /translation="MKNVMSVSLVSRNVARKLLLVQLLVVIASGLLFSLKDPFWGVSAI
FT SGGLAVFLPNVLFMIFAWRHQAHTPAKGRVAWTFAFGEAFKVLAMLVLLVVALAVLKAV
FT FLPLIVTWVLVLVVQILAPAVINNKG"
FT RBS 3979..3981
FT /note="pot. Shine Dalgarno region"
FT CDS 3986..4801
FT /transl_table=11
FT /note="uncB protein"
FT /db_xref="GOA:P0AB98"
FT /db_xref="InterPro:IPR000568"
FT /db_xref="PDB:1C17"
FT /db_xref="UniProtKB/Swiss-Prot:P0AB98"
FT /protein_id="CAA25776.1"
FT /translation="MASENMTPQDYIGHHLNNLQLDLRTFSLVDPQNPPATFWTINIDS
FT MFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPL
FT ALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFILILF
FT YSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIF
FT ILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH"
FT RBS 4838..4841
FT /note="pot. Shine Dalgarno region"
FT CDS 4848..5087
FT /transl_table=11
FT /note="uncE protein"
FT /db_xref="GOA:P68699"
FT /db_xref="InterPro:IPR000454"
FT /db_xref="InterPro:IPR002379"
FT /db_xref="InterPro:IPR005953"
FT /db_xref="PDB:1A91"
FT /db_xref="PDB:1ATY"
FT /db_xref="PDB:1C0V"
FT /db_xref="PDB:1C17"
FT /db_xref="PDB:1C99"
FT /db_xref="PDB:1IJP"
FT /db_xref="PDB:1J7F"
FT /db_xref="PDB:1L6T"
FT /db_xref="PDB:1QO1"
FT /db_xref="UniProtKB/Swiss-Prot:P68699"
FT /protein_id="CAA25777.1"
FT /translation="MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDL
FT IPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA"
FT RBS 5146..5149
FT /note="pot. Shine Dalgarno region"
FT CDS 5149..5619
FT /transl_table=11
FT /note="uncF protein"
FT /db_xref="GOA:P0ABA0"
FT /db_xref="InterPro:IPR002146"
FT /db_xref="InterPro:IPR005864"
FT /db_xref="PDB:1B9U"
FT /db_xref="PDB:1L2P"
FT /db_xref="UniProtKB/Swiss-Prot:P0ABA0"
FT /protein_id="CAA25778.1"
FT /translation="MNLNATILGQAIAFVLFVLFCMKYVWPPLMAAIEKRQKEIADGLA
FT SAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRSQILDEAKAEAEQERTKIVAQ
FT AQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL"
FT RBS 5619..5622
FT /note="pot. Shine Dalgarno region"
FT RBS 5625..5628
FT /note="pot. Shine Dalgarno region"
FT CDS 5634..6167
FT /transl_table=11
FT /note="uncH protein"
FT /db_xref="GOA:P0ABA4"
FT /db_xref="InterPro:IPR000711"
FT /db_xref="PDB:1ABV"
FT /db_xref="PDB:2A7U"
FT /db_xref="UniProtKB/Swiss-Prot:P0ABA4"
FT /protein_id="CAA25779.1"
FT /translation="MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQMA
FT ELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAVSE
FT ATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVIDGS
FT VRGRLERLADVLQS"
FT RBS 6175..6178
FT /note="pot. Shine Dalgarno region"
FT CDS 6180..7721
FT /transl_table=11
FT /note="uncA protein"
FT /db_xref="GOA:P0ABB0"
FT /db_xref="PDB:1D8S"
FT /db_xref="UniProtKB/Swiss-Prot:P0ABB0"
FT /protein_id="CAA25780.1"
FT /translation="MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLA
FT DCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLL
FT GRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQ
FT RELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTI
FT VVVATASESAALQYLARMPVALMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPP
FT GREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAF
FT VPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQ
FT YRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLAD
FT VELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQSW"
FT repeat_unit 7726..7753
FT /note="pot. hairpin structure"
FT RBS 7761..7764
FT /note="pot. Shine Dalgarno region"
FT CDS 7772..8635
FT /transl_table=11
FT /note="uncG protein"
FT /db_xref="GOA:P0ABA6"
FT /db_xref="InterPro:IPR000131"
FT /db_xref="PDB:1D8S"
FT /db_xref="PDB:1FS0"
FT /db_xref="UniProtKB/Swiss-Prot:P0ABA6"
FT /protein_id="CAA25781.1"
FT /translation="MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPY
FT AETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMK
FT TWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEG
FT RLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDTLLRR
FT YVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIV
FT SGAAAV"
FT RBS 8652..8655
FT /note="pot. Shine Dalgarno region"
FT CDS 8662..10044
FT /transl_table=11
FT /note="uncD protein"
FT /db_xref="GOA:P0ABB4"
FT /db_xref="InterPro:IPR000194"
FT /db_xref="InterPro:IPR000793"
FT /db_xref="InterPro:IPR003593"
FT /db_xref="InterPro:IPR004100"
FT /db_xref="InterPro:IPR005722"
FT /db_xref="PDB:1D8S"
FT /db_xref="UniProtKB/Swiss-Prot:P0ABB4"
FT /protein_id="CAA25782.1"
FT /translation="MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQ
FT QLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGE
FT EERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMEL
FT IRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVAL
FT TGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQE
FT RITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDS
FT TSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQR
FT FLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAK
FT KL"
FT RBS 10057..10059
FT /note="pot. Shine Dalgarno region"
FT CDS 10065..10484
FT /transl_table=11
FT /note="uncC protein"
FT /db_xref="GOA:P0A6E6"
FT /db_xref="InterPro:IPR001469"
FT /db_xref="PDB:1AQT"
FT /db_xref="PDB:1BSH"
FT /db_xref="PDB:1BSN"
FT /db_xref="PDB:1FS0"
FT /db_xref="PDB:1QO1"
FT /db_xref="UniProtKB/Swiss-Prot:P0A6E6"
FT /protein_id="CAA25783.1"
FT /translation="MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTA
FT IKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKAEE
FT HISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM"
FT misc_signal 10502..10532
FT /note="pot. hairpin structure, pot. transcriptional
FT terminator for uncC"
FT RBS 10828..10831
FT /note="pot. Shine Dalgarno region"
FT CDS 10837..12207
FT /transl_table=11
FT /note="Eco urf 1 protein"
FT /db_xref="GOA:P0ACC7"
FT /db_xref="PDB:1FWY"
FT /db_xref="PDB:1FXJ"
FT /db_xref="PDB:1HV9"
FT /db_xref="UniProtKB/Swiss-Prot:P0ACC7"
FT /protein_id="CAA25784.1"
FT /translation="MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAANE
FT LGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILMLYG
FT DVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATDEQR
FT QIQEINTGILIANGADMKRWLANVTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSE
FT VEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDTNVIIE
FT GNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRPGAELLE
FT GAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKFKTIIGD
FT DVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWRRPVKKK"
FT RBS 12357..12359
FT /note="pot. Shine Dalgarno region"
FT CDS 12369..14198
FT /transl_table=11
FT /note="gluS protein"
FT /db_xref="GOA:P17169"
FT /db_xref="PDB:1JXA"
FT /db_xref="PDB:1MOQ"
FT /db_xref="PDB:1MOR"
FT /db_xref="PDB:1MOS"
FT /db_xref="PDB:1XFF"
FT /db_xref="PDB:1XFG"
FT /db_xref="PDB:2BPJ"
FT /db_xref="PDB:2BPL"
FT /db_xref="UniProtKB/Swiss-Prot:P17169"
FT /protein_id="CAA25785.1"
FT /translation="MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTR
FT LRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGIIEN
FT HEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMD
FT SRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRRSVNI
FT FDKTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSE
FT LGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYRKSAVRR
FT NSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIG
FT VASTKAFTTQLTVLLMLVANVSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEAL
FT AEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPV
FT IVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMPHVEEVIAPIF
FT YTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE"
FT misc_signal 14207..14227
FT /note="pot. transcriptional terminator for gluS"
FT misc_feature 14223..14224
FT /note="Tn7 insertion site"
FT promoter 14357..14362
FT /note="pot. promoter -35 region"
FT promoter 14379..14383
FT /note="pot. promoter -10 region"
FT RBS 14502..14505
FT /note="pot. Shine Dalgarno region"
FT CDS 14512..>14526
FT /transl_table=11
FT /note="phoS protein"
FT /protein_id="CAA25786.1"
FT /translation="MKVMR"
XX
SQ Sequence 14526 BP; 3545 A; 3594 C; 3860 G; 3527 T; 0 other;
gggatcgtgg gttaatttac tcaaataagt atacagatcg tgcgatctac tgtggataac 60
tctgtcagga agcttggatc aaccggtagt tatccaaaga acaactgttg ttcagttttt 120
gagttgtgta taacccctca ttctgatccc agcttatacg gtccaggatc accgatcatt 180
cacagttaat gatcctttcc aggttgttga tcttaaaagc cggatccttg ttatccacag 240
ggcagtgcga tcctaataag agatcacaat agaacagatc tctaaataaa tagatcttct 300
ttttaatacc caggatccca ggtctttctc aagccgacaa agttgagtag aatccacggc 360
ccgggcttca atccattttc ataccgcgtt atgcgaggca atcaccatgt tttatccgga 420
tccttttgac gtcatcatca ttggcggggg tcatgcaggc accgaggccg cgatggccgc 480
ggcgcgtatg ggtcaacaga ctctgctttt gacacacaat atcgacactc tggggcagat 540
gagctgcaac ccggcgatcg gcggtattgg gaagggacat ctggtaaaag aagtggatgc 600
actcggcggt ctgatggcga aagcgatcga tcaggcgggt atccagttta ggatactaaa 660
cgcaagcaaa ggaccggcgg ttcgcgctac ccgagctcag gcggatcgtg tgctctaccg 720
tcaggcggta cgtacggcgc tggagaacca accgaacctg atgatcttcc agcaggcggt 780
tgaagatctt attgtcgaaa acgatcgcgt ggtcggtgct gttacccaaa tgggactgaa 840
gttccgtgcc aaagccgtcg tgctcaccgt tgggacgttc ctcgacggta aaattcatat 900
cggtctggat aattacagcg gtggccgtgc tggtgatccg ccgtccattc cgctttctcg 960
ccgtttgcgt gaactgccgc tgcgcgttgg tcgtctgaaa accgggacac caccgcgtat 1020
tgatgctcga accatcgact ttagcgtact ggcgcaacag catggcgata acccaatgcc 1080
ggtattctcg tttatgggca atgcgtccca gcatccccag caggtgccgt gttatatcac 1140
tcataccaac gagaaaaccc atgatgtgat ccgcagtaac ctcgatcgta gcccaatgta 1200
cgcaggggtg atcgaaggtg tcggcccacg ctactgcccg tcgatcgaag acaaagtcat 1260
gcgcttcgcc gacagaaatc agcatcagat cttccttgaa ccggaaggac tgacctctaa 1320
tgaaatttat ccgaacggta tctccaccag cctgccgttc gatgtgcaga tgcaaatcgt 1380
ccgctctatg caggggatgg aaaacgcgaa gatcgtgcgt ccgggttatg ccattgagta 1440
tgacttcttc gatcctcgcg acctgaaacc gacgctggag agcaagttta tccaggggct 1500
gttctttgct ggtcagatta acggcactac cggttacgaa gaagccgctg cgcaaggttt 1560
gctggccggt cttaacgctg cccgtctgtc tgctgacaaa gaaggttggg ctccggcacg 1620
ttctcaggcg tatctcggcg tactagttga tgacctgtgc actttaggaa ccaaagaacc 1680
gtatcgtatg tttacttcgc gcgcagaata tcgtctgatg ctacgcgaag ataatgcgga 1740
tctgcgtttg actgaaatcg gtcgtgaact gggcctggtg gatgacgaac gttgggcgcg 1800
ctttaacgag aaacttgaga atatcgagcg tgagcgtcag cgtctgaaat cgacctgggt 1860
aaccccgtcg gcggaagctg cagccgaagt gaatgctcac ctgactgcgc cgctttcccg 1920
tgaagccagt ggtgaagatc tgctgcgtcc ggaaatgact tatgaaaaat taaccacgct 1980
gacgccgttt gcccctgcgt tgacagacga acaggcggcg gaacaggttg agattcaggt 2040
taaatacgaa ggttatatcg cgcgccagca agatgagatc gaaaagcagc tgcgtaacga 2100
gaacaccctg ctacccgcga cactggatta ccgccaggta tccggtcttt ctaacgaagt 2160
gatcgccaaa cttaacgatc acaaaccagc ctctatcggc caagcttcgc gtatttctgg 2220
cgtcacgcct gcggccatct ccattctgct ggtgtggctg aaaaaacagg gtatgctgcg 2280
tcgtagcgca taacgcatta aaaatgcctg gtaagcaccc gcttaccagg caacgcatca 2340
agaacaggta atcaccgtgc tcaacaaact ctccttactg ctgaaagacg caggtatttc 2400
gcttaccgat caccagaaaa accagcttat tgcctacgtg aatatgctgc ataaatggaa 2460
caaagcgtac aacctgactt cggtccgcga tcctaatgag atgctggtac gccatattct 2520
cgatagcatt gtggtggcac cgtatctgca aggtgaacgg tttatcgatg tcggcaccgg 2580
accaggactg ccaggcattc cactctctat cgtgcgtcct gaagcccatt tcactctgtt 2640
ggatagcctt ggtaaacgcg tgcgtttcct tcgtcaggtg caacatgagc ttaaactgga 2700
gaatattgaa ccagtacaga gcagggtaga agagtttcct tcagagccgc catttgatgg 2760
cgtaattagc cgcgcttttg cctctctgaa cgatatggtg agctggtgcc accatcttcc 2820
tggtgagcaa ggccgtttct acgcgctgaa agggcaaatg ccggaagatg aaatcgcttt 2880
gttgcccgaa gaatatcagg tcgaatcagt ggttaaactt caggttccag ccctggatgg 2940
cgaacgtcat ctggtggtga ttaaagcaaa taaaatttaa tttttatcaa aaaaatcata 3000
aaaaattgac cggttagact gttaacaaca accaggtttt ctactgatat aactggttac 3060
atttaacgcc acgttcactc ttttgcatca acaagataac gtggcttttt ttggtaagca 3120
gaaaataagt cattagtgaa aatatcagtc tgctaaaaat cggcgctaag aaccatcatt 3180
ggctgttaaa acattattaa aaatgtcaat gggtggtttt tgttgtgtaa atgtcattta 3240
ttaaaacagt atctgttttt agactgaaat atcataaact tgcaaaggca tcatttgcca 3300
agtaaataaa tatgctgtgc gcgaacatgc gcaatatgtg atctgaagca cgctttatca 3360
ccagtgttta cgcgttattt acagtttttc atgatcgaac agggttagca gaaaagtcgc 3420
aattgtatgc actggaaaaa tatttaaaca tttattcacc ttttggctac ttattgtttg 3480
aaatcacggg ggcgcaccgt ataatttgac cgctttttga tgcttgactc taagccttaa 3540
agaaagtttt atacgacacg cggcatacct cgaagggagc aggagtgaaa aacgtgatgt 3600
ctgtgtcgct cgtgagtcga aacgttgctc ggaagcttct gctcgttcag ttactggtgg 3660
tgatagcaag tggattgctg ttcagcctca aagacccctt ctggggcgtc tctgcaataa 3720
gcgggggcct ggcagtcttt ctgcctaacg ttttgtttat gatatttgcc tggcgtcacc 3780
aggcgcatac accagcgaaa ggccgggtgg cctggacatt cgcatttggc gaagctttca 3840
aagttctggc gatgttggtg ttactggtgg tggcgttggc ggttttaaag gcggtattct 3900
tgccgctgat cgttacgtgg gttttggtgc tggtggttca gatactggca ccggctgtaa 3960
ttaacaacaa agggtaaaag gcatcatggc ttcagaaaat atgacgccgc aggattacat 4020
aggacaccac ctgaataacc ttcagctgga cctgcgtaca ttctcgctgg tggatccaca 4080
aaacccccca gccaccttct ggacaatcaa tattgactcc atgttcttct cggtggtgct 4140
gggtctgttg ttcctggttt tattccgtag cgtagccaaa aaggcgacca gcggtgtgcc 4200
aggtaagttt cagaccgcga ttgagctggt gatcggcttt gttaatggta gcgtgaaaga 4260
catgtaccat ggcaaaagca agctgattgc tccgctggcc ctgacgatct tcgtctgggt 4320
attcctgatg aacctgatgg atttactgcc tatcgacctg ctgccgtaca ttgctgaaca 4380
tgtactgggt ctgcctgcac tgcgtgtggt tccgtctgcg gacgtgaacg taacgctgtc 4440
tatggcactg ggcgtattta tcctgattct gttctacagc atcaaaatga aaggcatcgg 4500
cggcttcacg aaagagttga cgctgcagcc gttcaatcac tgggcgttca ttcctgtcaa 4560
cttaatcctt gaaggggtaa gcctgctgtc caaaccagtt tcactcggtt tgcgactgtt 4620
cggtaacatg tatgccggtg agctgatttt cattctgatt gctggtctgt tgccgtggtg 4680
gtcacagtgg atcctgaatg tgccgtgggc cattttccac atcctgatca ttacgctgca 4740
agccttcatc ttcatggttc tgacgatcgt ctatctgtcg atggcgtctg aagaacatta 4800
atttaccaac actactacgt tttaactgaa acaaactgga gactgtcatg gaaaacctga 4860
atatggatct gctgtacatg gctgccgctg tgatgatggg tctggcggca atcggtgctg 4920
cgatcggtat cggcatcctc gggggtaaat tcctggaagg cgcagcgcgt caacctgatc 4980
tgattcctct gctgcgtact cagttcttta tcgttatggg tctggtggat gctatcccga 5040
tgatcgctgt aggtctgggt ctgtacgtga tgttcgctgt cgcgtagtaa gcgttgcttt 5100
tatttaaaga gcaatatcag aacgttaact aaatagaggc attgtgctgt gaatcttaac 5160
gcaacaatcc tcggccaggc catcgcgttt gtcctgttcg ttctgttctg catgaagtac 5220
gtatggccgc cattaatggc agccatcgaa aaacgtcaaa aagaaattgc tgacggcctt 5280
gcttccgcag aacgagcaca taaggacctt gaccttgcaa aggccagcgc gaccgaccag 5340
ctgaaaaaag cgaaagcgga agcccaggta atcatcgagc aggcgaacaa acgccgctcg 5400
cagattctgg acgaagcgaa agctgaggca gaacaggaac gtactaaaat cgtggcccag 5460
gcgcaggcgg aaattgaagc cgagcgtaaa cgtgcccgtg aagagctgcg taagcaagtt 5520
gctatcctgg ctgttgctgg cgccgagaag atcatcgaac gttccgtgga tgaagctgct 5580
aacagcgaca tcgtggataa acttgtcgct gaactgtaag gagggagggg ctgatgtctg 5640
aatttattac ggtagctcgc ccctacgcca aagcagcttt tgactttgcc gtcgaacacc 5700
aaagtgtaga acgctggcag gacatgctgg cgtttgccgc cgaggtaacc aaaaacgaac 5760
aaatggcaga gcttctctct ggcgcgcttg cgccagaaac gctcgccgag tcgtttatcg 5820
cagtttgtgg tgagcaactg gacgaaaacg gtcagaacct gattcgggtt atggctgaaa 5880
atggtcgtct taacgcgctc ccggatgttc tggagcagtt tattcacctg cgtgccgtga 5940
gtgaggctac cgctgaggta gacgtcattt ccgctgccgc actgagtgaa caacagctcg 6000
cgaaaatttc tgctgcgatg gaaaaacgtc tgtcacgcaa agttaagctg aattgcaaaa 6060
tcgataagtc tgtaatggca ggcgttatca tccgagcggg tgatatggtc attgatggca 6120
gcgtacgcgg tcgtcttgag cgccttgcag acgtcttgca gtcttaaggg gactggagca 6180
tgcaactgaa ttccaccgaa atcagcgaac tgatcaagca gcgcattgct cagttcaatg 6240
ttgtgagtga agctcacaac gaaggtacta ttgtttctgt aagtgacggt gttatccgca 6300
ttcacggcct ggccgattgt atgcagggtg aaatgatctc cctgccgggt aaccgttacg 6360
ctatcgcact gaacctcgag cgcgactctg taggtgcggt tgttatgggt ccgtacgctg 6420
accttgccga aggcatgaaa gttaagtgta ctggccgtat cctggaagtt ccggttggcc 6480
gtggcctgct gggccgtgtg gttaacactc tgggtgcacc aatcgacggt aaaggtccgc 6540
tggatcacga cggcttctct gctgtagaag caatcgctcc gggcgttatc gaacgtcagt 6600
ccgtagatca gccggtacag accggttata aagccgttga ctccatgatc ccaatcggtc 6660
gtggtcagcg tgaattgatc atcggtgacc gtcagacagg taaaaccgca ctggctatcg 6720
atgccatcat caaccagcgc gattccggta tcaaatgtat ctatgtcgct atcggccaga 6780
aagcgtccac catttctaac gtggtacgta aactggaaga gcacggcgca ctggctaaca 6840
ccatcgttgt ggtagcaacc gcgtctgaat ccgctgcact gcaatacctg gcacgtatgc 6900
cggttgcgct aatgggcgaa tacttccgtg accgcggtga agatgcgctg atcatttacg 6960
atgacctgtc taaacaggct gttgcttacc gtcagatctc cctgctgctc cgtcgtccgc 7020
caggacgtga agcattcccg ggcgacgttt tctacctcca ctctcgtctg ctggagcgtg 7080
ctgcacgtgt taacgccgaa tacgttgaag ccttcaccaa aggtgaagtg aaagggaaaa 7140
ccggttctct gaccgcactg ccgattatcg aaactcaggc gggtgacgtt tctgcgttcg 7200
ttccgaccaa cgtaatctcc attaccgatg gtcagatctt cctggaaacc aacctgttca 7260
acgccggtat tcgtcctgcg gttaacccgg gtatttccgt atcccgtgtt ggtggtgcag 7320
cacagaccaa gatcatgaaa aaactgtccg gtggtatccg taccgctctg gcacagtatc 7380
gtgaactggc agcgttctct cagtttgcat ccgaccttga cgatgcaaca cgtaagcagc 7440
ttgaccacgg tcagaaagtg accgaactgc tgaaacagaa acagtatgcg ccgatgtccg 7500
ttgcgcagca gtctctggtt ctgttcgcag cagaacgtgg ttacctggcg gatgttgaac 7560
tgtcgaaaat tggcagcttc gaagccgctc tgctggctta cgtcgaccgt gatcacgctc 7620
cgttgatgca agagatcaac cagaccggtg gctacaacga cgaaatcgaa ggcaagctga 7680
aaggcatcct cgattccttc aaagcaaccc aatcctggta acgtctggcg gcttgcctta 7740
gggcaggccg caaggcattg aggagaagct catggccggc gcaaaagaga tacgtagtaa 7800
gatcgcaagc gtccagaaca cgcaaaagat cactaaagcg atggagatgg tcgccgcttc 7860
caaaatgcgt aaatcgcagg atcgcatggc ggccagccgt ccttatgcag aaaccatgcg 7920
caaagtgatt ggtcaccttg cacacggtaa tctggaatat aagcaccctt acctggaaga 7980
ccgcgacgtt aaacgcgtgg gctacctggt ggtgtcgacc gaccgtggtt tgtgcggtgg 8040
tttgaacatt aacctgttca aaaaactgct ggcggaaatg aagacctgga ccgacaaagg 8100
cgttcaatgc gacctcgcaa tgatcggctc gaaaggcgtg tcgttcttca actccgtggg 8160
cggcaatgtt gttgcccagg tcaccggcat gggggataac ccttccctgt ccgaactgat 8220
cggtccggta aaagtgatgt tgcaggccta cgacgaaggc cgtctggaca agctttacat 8280
tgtcagcaac aaatttatta acaccatgtc tcaggttccg accatcagcc agctgctgcc 8340
gttaccggca tcagatgatg atgatctgaa acataaatcc tgggattacc tgtacgaacc 8400
cgatccgaag gcgttgctgg ataccctgct gcgtcgttat gtcgaatctc aggtttatca 8460
gggcgtggtt gaaaacctgg ccagcgagca ggccgcccgt atggtggcga tgaaagccgc 8520
gaccgacaat ggcggcagcc tgattaaaga gctgcagttg gtatacaaca aagctcgtca 8580
ggccagcatt actcaggaac tcaccgagat cgtctcgggg gccgccgcgg tttaaacagg 8640
ttatttcgta gaggatttaa gatggctact ggaaagattg tccaggtaat cggcgccgta 8700
gttgacgtcg aattccctca ggatgccgta ccgcgcgtgt acgatgctct tgaggtgcaa 8760
aatggtaatg agcgtctggt gctggaagtt cagcagcagc tcggcggcgg tatcgtacgt 8820
accatcgcaa tgggttcctc cgacggtctg cgtcgcggtc tggatgtaaa agacctcgaa 8880
cacccgattg aagtcccggt aggtaaagcg actctgggcc gtatcatgaa cgtactgggt 8940
gaaccggtcg acatgaaagg cgagatcggt gaagaagagc gttgggcgat tcaccgcgca 9000
gcaccttcct acgaagagct gtcaaactct caggaactgc tggaaaccgg tatcaaagtt 9060
atcgacctga tgtgtccgtt cgctaagggc ggtaaagttg gtctgttcgg tggtgcgggt 9120
gtaggtaaaa ccgtaaacat gatggagctc attcgtaaca tcgcgatcga gcactccggt 9180
tactctgtgt ttgcgggcgt aggtgaacgt actcgtgagg gtaacgactt ctaccacgaa 9240
atgaccgact ccaacgttat cgacaaagta tccctggtgt atggccagat gaacgagccg 9300
ccgggaaacc gtctgcgcgt tgctctgacc ggtctgacca tggctgagaa attccgtgac 9360
gaaggtcgtg acgttctgct gttcgttgac aacatctatc gttacaccct ggccggtacg 9420
gaagtatccg cactgctggg ccgtatgcct tcagcggtag gttatcagcc gaccctggcg 9480
gaagagatgg gcgttctgca ggaacgtatc acctccacca aaactggttc tatcacctcc 9540
gtacaggcag tatacgtacc tgcggatgac ttgactgacc cgtctccggc aaccaccttt 9600
gcgcaccttg acgcaaccgt ggtactgagc cgtcagatcg cgtctctggg tatctacccg 9660
gccgttgacc cgctggactc caccagccgt cagctggacc cgctggtggt tggtcaggaa 9720
cactacgaca ccgcgcgtgg cgttcagtcc atcctgcaac gttatcagga actgaaagac 9780
atcatcgcca tcctgggtat ggatgaactg tctgaagaag acaaactggt ggtagcgcgt 9840
gctcgtaaga tccagcgctt cctgtcccag ccgttcttcg tggcagaagt attcaccggt 9900
tctccgggta aatacgtctc cctgaaagac accatccgtg gctttaaagg catcatggaa 9960
ggcgaatacg atcacctgcc ggagcaggcg ttctacatgg tcggttccat cgaagaagct 10020
gtggaaaaag ccaaaaaact ttaacgcctt aatcggaggg tgatatggca atgacttacc 10080
acctggacgt cgtcagcgca gagcaacaaa tgttctctgg tctggtcgag aaaatccagg 10140
taacgggtag cgaaggtgaa ctggggatct accctggcca cgcaccgctg ctcaccgcca 10200
ttaagcctgg tatgattcgc atcgtgaaac agcacggtca cgaagagttt atctatctgt 10260
ctggcggcat tcttgaagtg cagcctggca acgtgaccgt tctggccgac accgcaattc 10320
gcggccagga tctcgacgaa gcgcgagcca tggaagcgaa acgtaaggct gaagagcaca 10380
ttagcagctc tcacggcgac gtagattacg ctcaggcgtc tgcggaactg gccaaagcga 10440
tcgcgcagct gcgcgttatc gagttgacca aaaaagcgat gtaacaccgg cttgaaaagc 10500
acaaaagcca gtctggaaac aggctggctt ttttttgcgc gtgtgacccg tcctgaatag 10560
cgttcacata gatcctgctg atataaaacc cccctgtttt cctgtttatt cattgatcga 10620
aataagagca aaaacatcca cctgacgctt aaattaaggt actgccttaa ttttctgcag 10680
acaaaaggcg tgacgatggt cgaaaatggc gctttcgtca gcggggataa tccgttattg 10740
aacaatttat cctctgtcca tttcacgatg aaaaaaatgt agttttttca aggtgaagcg 10800
gtttaaattc gttctcaaat tacagtcagg acgcgtatgt tgaataatgc tatgagcgta 10860
gtgatccttg ccgcaggcaa aggcacgcgc atgtattccg atcttccgaa agtgctgcat 10920
acccttgccg ggaaagcgat ggttcagcat gtcattgatg ctgcgaatga attaggcgca 10980
gcgcacgttc acctggtgta cggtcacggc ggcgatctgc taaaacaggc gctgaaagac 11040
gacaacctta actgggtgct tcaggcagag cagctgggta cgggtcatgc aatgcagcag 11100
gccgcacctt tctttgccga tgatgaagac attttaatgc tctacggcga cgtgccgctg 11160
atctctgtcg aaacactcca gcgtctgcgt gatgctaaac cgcagggtgg cattggtctg 11220
ctgacggtga aactggatga tccgaccggt tatggacgta tcacccgtga aaacggcaaa 11280
gttaccggca ttgttgagca caaagatgcc accgacgagc agcgtcagat tcaggagatc 11340
aacaccggca ttctgattgc caacggcgca gatatgaaac gctggctggc gaacgtgacc 11400
aacaataatg ctcagggcga atactacatc accgacatta ttgcgctggc gtatcaggaa 11460
gggcgtgaaa tcgtcgccgt tcatccgcaa cgtttaagcg aagtagaagg cgtgaataac 11520
cgcctgcaac tctcccgtct ggagcgtgtt tatcagtccg aacaggctga aaaactgctg 11580
ttagcaggcg ttatgctgcg cgatccagcg cgttttgatc tgcgtggtac gctaactcac 11640
gggcgcgatg ttgaaattga tactaacgtt atcatcgagg gcaacgtgac tctcggtcat 11700
cgcgtgaaaa ttggcaccgg ttgcgtgatt aaaaacagcg tgattggcga tgattgcgaa 11760
atcagtccgt ataccgttgt ggaagatgcg aatctggcag cggcctgtac cattggcccg 11820
tttgcccgtt tgcgtcctgg tgctgagttg ctggaaggtg ctcacgtcgg taacttcgtt 11880
gagatgaaaa aagcgcgtct gggtaaaggc tcgaaagctg gtcatctgac ttacctgggc 11940
gatgcggaaa ttggcgataa cgttaacatc ggcgcgggaa ccattacctg caactacgat 12000
ggtgcgaata aatttaagac cattatcggc gacgatgtgt ttgttggttc cgacactcag 12060
ctggtggccc cggtaacagt aggcaaaggc gcgaccattg ctgcgggtac aactgtgacg 12120
cgtaatgtcg gcgaaaatgc attagctatc agccgtgtgc cgcagactca gaaagaaggc 12180
tggcgtcgtc cggtaaagaa aaagtgattc tggccggcta acccggtcac atgggatgag 12240
gagataacat aatctccctc ccacaagcag taactataaa aataacccca ctctctacaa 12300
ggctcggggc gcccgaaaaa acgggcatac aggttgaccg acaacgatat aaatcggaat 12360
caaaaactat gtgtggaatt gttggcgcga tcgcgcaacg tgatgtagca gaaatccttc 12420
ttgaaggttt acgtcgtctg gaataccgcg gatatgactc tgccggtctg gccgttgttg 12480
atgcagaagg tcatatgacc cgcctgcgtc gcctcggtaa agtccagatg ctggcacagg 12540
cagcggaaga acatcctctg catggcggca ctggtattgc tcacactcgc tgggcgaccc 12600
acggtgaacc ttcagaagtg aatgcgcatc cgcatgtttc tgaacacatt gtggtggtgc 12660
ataacggcat catcgaaaac catgaaccgc tgcgtgaaga gctaaaagcg cgtggctata 12720
ccttcgtttc tgaaaccgac accgaagtga ttgcccatct ggtgaactgg gagctgaaac 12780
aaggcgggac tctgcgtgag gccgttctgc gtgctatccc gcagctgcgt ggtgcgtacg 12840
gtacagtgat catggactcc cgtcacccgg ataccctgct ggcggcacgt tctggtagtc 12900
cgctggtgat tggcctgggg atgggcgaaa actttatcgc ttctgaccag ctggcgctgt 12960
tgccggtgac ccgtcgcttt atcttccttg aagagggcga tattgcggaa atcactcgcc 13020
gttcggtaaa catcttcgat aaaactggcg cggaagtaaa acgtcaggat atcgaatcca 13080
atctgcaata tgacgcgggc gataaaggca tttaccgtca ctacatgcag aaagagatct 13140
acgaacagcc gaacgcgatc aaaaacaccc ttaccggacg catcagccac ggtcaggttg 13200
atttaagcga gctgggaccg aacgccgacg aactgctgtc gaaggttgag catattcaga 13260
tcctcgcctg tggtacttct tataactccg gtatggtttc ccgctactgg tttgaatcgc 13320
tagcaggtat tccgtgcgac gtcgaaatcg cctctgaatt ccgctatcgc aaatctgccg 13380
tgcgtcgtaa cagcctgatg atcaccttgt cacagtctgg cgaaaccgcg gataccctgg 13440
ctggcctgcg tctgtcgaaa gagctgggtt accttggttc actggcaatc tgtaacgttc 13500
cgggttcttc tctggtgcgc gaatccgatc tggcgctaat gaccaacgcg ggtacagaaa 13560
tcggcgtggc atccactaaa gcattcacca ctcagttaac tgtgctgttg atgctggtgg 13620
cgaacgtgtc tcgcctgaaa ggtctggatg cctccattga acatgacatc gtgcatggtc 13680
tgcaggcgct gccgagccgt attgagcaga tgctgtctca ggacaaacgc attgaagcgc 13740
tggcagaaga tttctctgac aaacatcacg cgctgttcct gggccgtggc gatcagtacc 13800
caatcgcgct ggaaggcgca ttgaagttga aagagatctc ttacattcac gctgaagcct 13860
acgctgctgg cgaactgaaa cacggtccgc tggcgctaat tgatgccgat atgccggtta 13920
ttgttgttgc accgaacaac gaattgctgg aaaaactgaa atccaacatt gaagaagttc 13980
gcgcgcgtgg cggtcagttg tatgtcttcg ccgatcagga tgcgggtttt gtaagtagcg 14040
ataacatgca catcatcgag atgccgcatg tggaagaggt gattgcaccg atcttctaca 14100
ccgttccgct gcagctgctg gcttaccatg tcgcgctgat caaaggcacc gacgttgacc 14160
agccgcgtaa cctggcaaaa tcggttacgg ttgagtaata aatggatgcc ctgcgtaagc 14220
ggggcatttt tcttcctgtt atgtttttaa tcaaacatcc tgccaactcc atgtgacaaa 14280
ccgtcatctt cggctacttt ttctctgtca cagaatgaaa atttttctgt catctcttcg 14340
ttattaatgt ttgtaattga ctgaatatca acgcttattt aaatcagact gaagacttta 14400
tctctctgtc ataaaactgt catattcctt acatataact gtcacctgtt tgtcctattt 14460
tgcttctcgt agccaacaaa caatgcttta tgaatcctcc caggagacat tatgaaagtt 14520
atgcgt 14526
//