Документ взят из кэша поисковой машины. Адрес оригинального документа : http://kodomo.fbb.msu.ru/hg/allpy/file/d137df18a8bf/test/usecase2.py
Дата изменения: Unknown
Дата индексирования: Mon Feb 4 05:39:36 2013
Кодировка:
allpy: d137df18a8bf test/usecase2.py

allpy

view test/usecase2.py @ 816:d137df18a8bf

structure: create method superimpose of SequenceMixin Most of code of AlignmentMixin.superimpose was moved to SequenceMixin. Structures of sequences can be superimposed manually (in custom order, or with additions action such as loading/unloading of structure).
author boris (kodomo) <bnagaev@gmail.com>
date Fri, 15 Jul 2011 02:06:23 +0400
parents bed32775625a
children ddf85d0a8924
line source
1 import sys
2 from allpy import dna
3 from allpy.processors import Needle, Left
4 from allpy.fileio import FastaFile
5 from collections import deque
7 width = 15
8 threshold = 10
10 def has_identity(column):
11 as_list = column.values()
12 return len(column) == 2 and as_list[0] == as_list[1]
14 def is_good_window(window):
15 sum_id = sum(int(has_identity(column)) for column in window)
16 return len(window) == width and sum_id >= threshold
18 def find_runs(alignment):
19 window = deque([], width)
20 blocks = []
21 in_block = False
22 for column in alignment.columns:
23 window.append(column)
24 in_block, was_in_block = is_good_window(window), in_block
25 if in_block and not was_in_block:
26 block = dna.Block.from_alignment(alignment, columns=list(window))
27 blocks.append(block)
28 elif in_block:
29 block.columns.append(column)
30 return blocks
32 def blocks_markup(alignment, blocks):
33 for column in alignment.columns:
34 column.in_block = "-"
35 for block in blocks:
36 for column in block.columns:
37 column.in_block = "+"
38 return "".join(column.in_block for column in alignment.columns)
40 def main():
41 alignment = dna.Alignment().append_file(sys.stdin)
42 assert len(alignment.sequences) == 2, "Input must have TWO sequences!"
43 alignment.realign(Left())
44 alignment.realign(Needle())
45 blocks = find_runs(alignment)
47 for n, block in enumerate(blocks, 1):
48 block.to_file(open("block_%02d.fasta" % n, "w"))
50 alignment.to_file(sys.stdout)
51 FastaFile(sys.stdout).write_string(
52 blocks_markup(alignment, blocks),
53 "markup",
54 "In run with window %s and threshold %s" % (width, threshold)
55 )
57 try:
58 main()
59 except Exception, e:
60 print "An error has occured:", e