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Prof. Eshel Ben-Jacob |
the head of the Tauber Initiative at Tel Aviv University and the Weizmann Institute,
Professor of Physics, The Maguy-Glass Professor in Physics of Complex Systems
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Dr. Leonid I. Brodsky |
Tel Aviv University and University Of Haifa
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Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel
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Vladimir Drachev - Group leader |
PhD, Deputy Director, A.N. Belozersky Institute of Physico-Chemical Biology.
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Mr. Vladimir K. Nikolaev |
Dr. Vladimir V. Galatenko |
Dr. Alexander A. Kravchenko |
Dr. Andrey M. Leontovich |
Mr. Timur S. Shakuov |
Mr. Alexander V. Nikonov |
Leninskye gory, 119899 Moscow, Russia
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Quality control, ORF detection and gene annotation of Paenibacillus
dendritiformis and Paenibacillus vortex genomes: |
- mapping reads/flowgrams against 454 contigs
- flowgram based quality control of contig positions and fragments
- the detection of the poor quality segments of contigs
- de Bruijn graph based reassembling of flowgrams/reads that are mapped to poor quality segments of contigs in order to reach the improvement of statistical quality of contigs and the uniform coverage of contig segments by reads
- the uniform coverage of contig segments by reads
- iterative correction of reassembly through the comparison of two in parallel assembled genomes, and contigs of independently sequenced third (P.Larvae) genome
- the extrinsic and intrinsic algorithms based prediction of ORFs
- iterative correction of assembly in order to improve ORF prediction for both genomes
- gene annotation by A4 algorithm
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References |
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