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... Anti thrombin DNA aptamers were immobilized on silica microspheres, placed inside microwells on the distal tip on an imaging optical fiber, coupled to a modified epifluorescence microscope through its proximal tip. ... It should be mentioned that since thrombin is not a DNA binding protein, the possibility to elicit thrombinґaptamer complexes clearly demonstrates the power of SELEX technology. ... Specificity of aptamer coated beads for F thrombin binding was assessed with bovine serum albumin. ...

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... 24 Assembly of 48S Translation Initiation Complexes from Purified Components with mRNAs That Have Some Base Pairing within Their 5 Untranslated Regions Sergei E. Dmitriev,1 Ilya M. Terenin,1 Yan E. Dunaevsky,1 William ... of Medicine, Cleveland, Ohio 44106-49352 Received 23 May 2003/Returned for modification 30 June 2003/Accepted 11 August 2003 The reconstitution of translation initiation ... Assembly and analysis of 48S translation initiation complexes. ...

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80. University Satellites and Space Science Education '2006